The average bus between Nieuwegein and Brussels takes 3h 51m and the fastest bus takes 3h 13m. The bus service runs several times per day from Nieuwegein to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Nieuwegein and Brussels. The earliest departure is at 6:14 AM in the morning, and the last departure from Nieuwegein is at 6:41 PM which arrives into Brussels at 10:35 PM. All services require a transfer, and take on average 3h 51m. The schedules shown below are for the next available departures.

3h 46m • 1 change
4h 8m • 1 change
3h 13m • 1 change
4h 2m • 1 changeWant to know about travelling from Nieuwegein to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Nieuwegein to Brussels. However, there are services departing from Utrecht Leidsche Rijn Centrum station and arriving at Brussels-North train station via Brussels-North train station. The journey, including transfers, takes approximately 3h 51m.
Nieuwegein to Brussels bus services, operated by FlixBus, depart from Utrecht Leidsche Rijn Centrum station.
Nieuwegein to Brussels bus services, operated by FlixBus, arrive at Brussels-North train station.
The distance between Nieuwegein and Brussels is 140.5 km. The road distance is 158 km.
FlixBus operates a bus from Utrecht Leidsche Rijn Centrum to Brussels-North train station every 4 hours. Tickets cost €14–22 and the journey takes 2h 50m.