The average bus between Niskayuna and Syracuse takes 3h 14m and the fastest bus takes 3h 6m. The bus service runs several times per day from Niskayuna to Syracuse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Niskayuna and Syracuse. The earliest departure is at 10:05 AM in the morning, and the last departure from Niskayuna is at 7:29 PM which arrives into Syracuse at 10:45 PM. All services require a transfer, and take on average 3h 14m. The schedules shown below are for the next available departures.

3h 35m • 1 change

3h 20m • 1 change

3h 20m • 1 change

3h 16m • 1 change

3h 17m • 1 change

3h 9m • 1 change

3h 6m • 1 change

3h 17m • 1 change
Want to know about travelling from Niskayuna to Syracuse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Niskayuna to Syracuse. However, there are services departing from Niskayuna station and arriving at Syracuse station via Syracuse. The journey, including transfers, takes approximately 3h 14m.
Niskayuna to Syracuse bus services, operated by Capital District Transportation (CDTA), depart from Schenectady station.
Niskayuna to Syracuse bus services, operated by Capital District Transportation (CDTA), arrive at Syracuse station.
The distance between Niskayuna and Syracuse is 189.8 km. The road distance is 224 km.
Trailways operates a bus from Schenectady to Syracuse twice daily. Tickets cost $25–80 and the journey takes 2h 35m. Two other operators also service this route.