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North Carolina to Des Moines buses

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Trip Overview

The bus between North Carolina and Des Moines takes 43h 55m. The bus runs, on average, 6 times per week from North Carolina to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

43h 55m
Duration
1,115 mi
Distance
$243
Average price
6 times a week
Frequency

North Carolina to Des Moines bus times

Buses run 6 times a week between North Carolina and Des Moines. The service departs North Carolina at 2:50 AM at night, which arrives into Des Moines at 21:45:00. All services require a transfer at Columbus and take an average of 43h 55m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA43h 55m • 2 changes

Departing Saturday, November 7, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA43h 55m • 2 changes

Departing Sunday, November 8, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA43h 55m • 2 changes

Departing Monday, November 9, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA43h 55m • 2 changes

Departing Tuesday, November 10, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA43h 55m • 2 changes

Frequently asked questions

Want to know about travelling from North Carolina to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from North Carolina to Des Moines.ExpandLaunch map view
  • Distance: 1,114.9 mi
  • Duration: 43h 55m

What companies run services between North Carolina, USA and Des Moines, IA, USA?

You can take a bus from Charlotte Bus Station to Des Moines via Columbus and Indianapolis Union Station in around 26h 5m.

Operators