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North Charleston to Roanoke buses

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Trip Overview

The bus between North Charleston and Roanoke takes 2d 1h. The bus runs, on average, 3 times per week from North Charleston to Roanoke. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 1h
Duration
594 mi
Distance
$126
Average price
3 times a week
Frequency

North Charleston to Roanoke bus times

Buses run 3 times a week between North Charleston and Roanoke. The service departs North Charleston at 10:40 AM in the morning, which arrives into Roanoke at 11:59:00. All services require a transfer at Raleigh Bus Station and take an average of 2d 1h. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USAGreyhound USA2d 1h • 3 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USAGreyhound USA2d 1h • 3 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USAGreyhound USA2d 1h • 3 changes

Frequently asked questions

Want to know about travelling from North Charleston to Roanoke? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from North Charleston to Roanoke.ExpandLaunch map view
  • Distance: 594.5 mi
  • Duration: 2d 1h

What companies run services between North Charleston, SC, USA and Roanoke, VA, USA?

You can take a bus from Charleston Bus Station to Roanoke Bus Stop via Raleigh Bus Station, Greensboro Bus Stop, and Lynchburg Transit Center in around 16h 34m.

Operators