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North Charleston to St. Louis buses

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Trip Overview

The bus between North Charleston and St. Louis takes 24h 20m. The bus runs, on average, 4 times per week from North Charleston to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

24h 20m
Duration
1,016 mi
Distance
$203
Average price
4 times a week
Frequency

North Charleston to St. Louis bus times

Buses run 4 times a week between North Charleston and St. Louis. The service departs North Charleston at 10:00 AM in the morning, which arrives into St. Louis at 09:20:00. All services require a transfer at Atlanta Bus Station and take an average of 24h 20m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA24h 20m • 2 changes

Departing Wednesday, November 11, 2026

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    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA24h 20m • 2 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA24h 20m • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA24h 20m • 2 changes

Frequently asked questions

Want to know about travelling from North Charleston to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from North Charleston to St. Louis.ExpandLaunch map view
  • Distance: 1,016.2 mi
  • Duration: 24h 20m

What companies run services between North Charleston, SC, USA and St. Louis, MO, USA?

You can take a bus from Charleston Bus Station to St Louis Bus Station via Atlanta Bus Station and Carbondale Intermodal Station in around 23h 51m.

Operators