The average bus between Northampton and Southampton takes 4h 44m and the fastest bus takes 3h 50m. The bus service runs several times per day from Northampton to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Northampton and Southampton. The earliest departure is at 4:35 AM at night, and the last departure from Northampton is at 1:00 PM which arrives into Southampton at 5:30 PM. All services require a transfer, and take on average 4h 44m. The schedules shown below are for the next available departures.

4h 20m • 1 change
4h 45m • 1 change
4h 40m • 1 change
4h 45m • 1 change
4h 35m • 1 change
5h 15m • 1 change
5h 20m • 1 change
4h 45m • 1 change
4h 35m • 1 change
5h 15m • 1 change
5h 20m • 1 change
4h 45m • 1 change
4h 35m • 1 change
5h 15m • 1 change
5h 20m • 1 change
4h 45m • 1 change
4h 35m • 1 change
5h 15m • 1 change
5h 20m • 1 change
4h 45m • 1 change
4h 35m • 1 change
4h 45m • 1 change
4h 40m • 1 change
5h • 1 changeWant to know about travelling from Northampton to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Northampton to Southampton. However, there are services departing from Northampton station and arriving at Southampton station via London Heathrow Airport. The journey, including transfers, takes approximately 4h 44m.
Northampton to Southampton bus services, operated by FlixBus, depart from Northampton Town Centre station.
Northampton to Southampton bus services, operated by FlixBus, arrive at Coach Station.
Book your Northampton to Southampton bus tickets online with FlixBus and National Express.
The distance between Northampton and Southampton is 153.9 km. The road distance is 218 km.
You can take a bus from Northampton Town Centre to Coach Station via Heathrow Central Bus Station in around 3h 58m.