The average bus between Novotel Berlin Mitte and Prague takes 4h 59m and the fastest bus takes 4h 33m. There is a bus service every few hours from Novotel Berlin Mitte to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Novotel Berlin Mitte and Prague. The earliest departure is at 3:43 AM at night, and the last departure from Novotel Berlin Mitte is at 11:42 PM which arrives into Prague at 4:40 AM. All services require a transfer at Fischerinsel and take an average of 4h 59m. The schedules shown below are for the next available departures.

4h 43m • 1 change

5h 3m • 1 change

5h 2m • 1 change

5h 3m • 1 change

5h 57m • 1 change

5h • 1 change

4h 41m • 1 change

5h 3m • 1 change

5h 57m • 1 change

5h • 1 change

4h 41m • 1 change

5h 3m • 1 change

5h 57m • 1 change

4h 59m • 1 change

4h 39m • 1 change

4h 56m • 1 change
Want to know about travelling from Novotel Berlin Mitte to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Novotel Berlin Mitte to Prague. However, there are services departing from Novotel Berlin Mitte station and arriving at Prague station via Praha, ÚAN Florenc. The journey, including transfers, takes approximately 4h 59m.
Novotel Berlin Mitte to Prague bus services, operated by BVG, depart from Berlin Südkreuz train station.
Novotel Berlin Mitte to Prague bus services, operated by BVG, arrive at Praha, ÚAN Florenc station.
The distance between Novotel Berlin Mitte and Prague is 278.7 km. The road distance is 339 km.
FlixBus operates a bus from Berlin Südkreuz train station to Praha, ÚAN Florenc hourly. Tickets cost Kč 650–1,200 and the journey takes 4h 5m.