Nové Mesto to Prague Buses

Nové Mesto to Prague buses

Travel from

Search accommodation with Expedia

Trip Overview

The average bus between Nové Mesto and Prague takes 4h 56m and the fastest bus takes 4h 35m. The bus service runs several times per day from Nové Mesto to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 56m
Duration: 342 km
Distance: Kč 877
Average price: Every 3 hours
Frequency

Bus

best

Take the bus from Bratislava, Autobusová stanica Mlynské Nivy to Praguebus 260 / ...

5h 30m

Kč 722–1,131

Nové Mesto to Prague bus times

Buses run every 3 hours between Nové Mesto and Prague. The earliest departure is at 4:42 AM at night, and the last departure from Nové Mesto is at 11:06 PM which arrives into Prague at 3:55 AM. All services require a transfer, and take on average 4h 56m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

4:42 AM → 10:40 AM
5h 58m • 1 change
7:35 AM → 12:20 PM
4h 45m • 1 change
9:15 AM → 2:05 PM
4h 50m • 1 change
11:15 AM → 4:05 PM
4h 50m • 1 change
Show more

Departing Wednesday, November 11, 2026

4:42 AM → 10:40 AM
5h 58m • 1 change
7:35 AM → 12:20 PM
4h 45m • 1 change
9:15 AM → 2:05 PM
4h 50m • 1 change
11:15 AM → 4:05 PM
4h 50m • 1 change
Show more

Departing Thursday, November 12, 2026

7:35 AM → 12:20 PM
4h 45m • 1 change
9:15 AM → 2:05 PM
4h 50m • 1 change
11:15 AM → 4:05 PM
4h 50m • 1 change
1:15 PM → 6:15 PM
5h • 1 change
Show more

Departing Friday, November 13, 2026

7:35 AM → 12:20 PM
4h 45m • 1 change
9:15 AM → 2:05 PM
4h 50m • 1 change
11:15 AM → 4:05 PM
4h 50m • 1 change
1:15 PM → 6:15 PM
5h • 1 change
Show more

Departing Saturday, November 14, 2026

4:45 AM → 10:40 AM
5h 55m • 1 change
7:15 AM → 12:20 PM
5h 5m • 1 change
9:15 AM → 2:05 PM
4h 50m • 1 change
11:15 AM → 4:05 PM
4h 50m • 1 change
Show more

Departing Sunday, November 15, 2026

4:45 AM → 10:40 AM
5h 55m • 1 change
7:15 AM → 12:20 PM
5h 5m • 1 change
9:15 AM → 2:05 PM
4h 50m • 1 change
11:15 AM → 4:05 PM
4h 50m • 1 change
Show more

Departing Monday, November 16, 2026

4:42 AM → 10:40 AM
5h 58m • 1 change
7:35 AM → 12:20 PM
4h 45m • 1 change
9:15 AM → 2:05 PM
4h 50m • 1 change
11:15 AM → 4:05 PM
4h 50m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Nové Mesto to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Nové Mesto to Prague buses

Find Transport to Prague

Trip Overview

Bus

Nové Mesto to Prague bus times

Departing Tuesday, November 10, 2026

4:42 AM → 10:40 AM

7:35 AM → 12:20 PM

9:15 AM → 2:05 PM

11:15 AM → 4:05 PM

Departing Wednesday, November 11, 2026

4:42 AM → 10:40 AM

7:35 AM → 12:20 PM

9:15 AM → 2:05 PM

11:15 AM → 4:05 PM

Departing Thursday, November 12, 2026

7:35 AM → 12:20 PM

9:15 AM → 2:05 PM

11:15 AM → 4:05 PM

1:15 PM → 6:15 PM

Departing Friday, November 13, 2026

7:35 AM → 12:20 PM

9:15 AM → 2:05 PM

11:15 AM → 4:05 PM

1:15 PM → 6:15 PM

Departing Saturday, November 14, 2026

4:45 AM → 10:40 AM

7:15 AM → 12:20 PM

9:15 AM → 2:05 PM

11:15 AM → 4:05 PM

Departing Sunday, November 15, 2026

4:45 AM → 10:40 AM

7:15 AM → 12:20 PM

9:15 AM → 2:05 PM

11:15 AM → 4:05 PM

Departing Monday, November 16, 2026

4:42 AM → 10:40 AM

7:35 AM → 12:20 PM

9:15 AM → 2:05 PM

11:15 AM → 4:05 PM

Frequently asked questions

What companies run services between Nové Mesto, Slovakia and Prague, Czechia?

Bus from Bratislava, Autobusová stanica Mlynské Nivy to Prague

Bus from Bratislava Central Bus Station to Prague Florenc Central Bus Station

Where to next?

Bus trips from Nové Mesto

Bus trips to Prague

Alternative transport options