The average bus between Nîmes and Sisteron takes 5h 48m and the fastest bus takes 4h 20m. The bus service runs several times per day from Nîmes to Sisteron. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Nîmes and Sisteron. The earliest departure is at 3:35 AM at night, and the last departure from Nîmes is at 9:35 PM which arrives into Sisteron at 9:45 AM. All services require a transfer, and take on average 5h 48m. The schedules shown below are for the next available departures.

4h 20m • 1 change
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4h 20m • 1 change
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6h 45m • 1 changeWant to know about travelling from Nîmes to Sisteron? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Nîmes to Sisteron. However, there are services departing from Nîmes - Parnasse Bus Station and arriving at Gare SNCF station via Marseille - Saint-Charles Bus Station. The journey, including transfers, takes approximately 5h 48m.
Nîmes to Sisteron bus services, operated by BlaBlaCar Bus, depart from Nîmes - Parnasse Bus Station.
Nîmes to Sisteron bus services, operated by Zou! Lignes Express Régionales, arrive at Gare SNCF station.
Book your Nîmes to Sisteron bus tickets online with Omio.
The distance between Nîmes and Sisteron is 133 km. The road distance is 171 km.
You can take a bus from Nîmes - Parnasse Bus Station to Gare SNCF via Gare Routière Saint-Charles in around 5h 15m.