The average bus between O'Hare and St. Louis takes 10h 6m and the fastest bus takes 7h 30m. The bus runs, on average, 6 times per week from O'Hare to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between O'Hare and St. Louis. The earliest departure is at 7:10 AM in the morning, and the last departure from O'Hare is at 8:10 AM which arrives into St. Louis at 3:40 PM. All services require a transfer, and take on average 10h 6m. The schedules shown below are for the next available departures.
Want to know about travelling from O'Hare to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from O'Hare to St. Louis. However, there are services departing from Chicago Bus Station and arriving at St Louis Bus Station via St Louis Bus Station. The journey, including transfers, takes approximately 10h 6m.
O'Hare to St. Louis bus services, operated by Flixbus USA, depart from Chicago Bus Station.
O'Hare to St. Louis bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
Book your O'Hare to St. Louis bus tickets online with Omio and FlixBus.
The distance between O'Hare and St. Louis is 422.4 km. The road distance is 477 km.
Flixbus USA operates a bus from Chicago Bus Station to St Louis Bus Station twice daily. Tickets cost $50–75 and the journey takes 5h 55m.
