The average bus between Oceanside and Otay Mesa takes 3h 43m and the fastest bus takes 2h 14m. The bus service runs several times per day from Oceanside to Otay Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Oceanside and Otay Mesa. The earliest departure is at 8:40 AM in the morning, and the last departure from Oceanside is at 11:05 PM which arrives into Otay Mesa at 5:03 AM. All services require a transfer at San Ysidro and take an average of 3h 43m. The schedules shown below are for the next available departures.


2h 39m • 2 changes


2h 19m • 2 changes
Arrives next day


5h 58m • 2 changes


2h 39m • 2 changes


2h 19m • 2 changes
Arrives next day


6h 50m • 2 changes


2h 14m • 2 changes


2h 24m • 2 changes
Arrives next day


7h 5m • 2 changes


2h 29m • 2 changes


2h 39m • 2 changes
Arrives next day


5h 58m • 2 changes


2h 39m • 2 changes


2h 19m • 2 changes
Arrives next day


5h 58m • 2 changes
Want to know about travelling from Oceanside to Otay Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Oceanside to Otay Mesa. However, there are services departing from Oceanside station and arriving at Otay Mesa station via San Ysidro. The journey, including transfers, takes approximately 3h 43m.
Oceanside to Otay Mesa bus services, operated by Greyhound Mexico, depart from Oceanside station.
Oceanside to Otay Mesa bus services, operated by Greyhound Mexico, arrive at San Ysidro station.
The distance between Oceanside and Otay Mesa is 79.3 km. The road distance is 97 km.
Greyhound Mexico operates a bus from Oceanside to San Ysidro 3 times a day. Tickets cost $13–17 and the journey takes 1h 20m.