The average bus between Oklahoma City and Lafayette takes 27h 47m and the fastest bus takes 23h 5m. The bus service runs several times per day from Oklahoma City to Lafayette. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Oklahoma City and Lafayette. The earliest departure is at 12:10 PM in the afternoon, and the last departure from Oklahoma City is at 9:45 PM which arrives into Lafayette at 6:35 AM. All services require a transfer at St Louis Bus Station and take an average of 27h 47m. The schedules shown below are for the next available departures.
Arrives next day


24h 5m • 2 changes
Arrives +2 days


32h 50m • 2 changes
Arrives next day


24h 5m • 2 changes
Arrives +2 days


32h 50m • 2 changes
Arrives next day


24h 5m • 2 changes
Arrives +2 days


32h 50m • 2 changes
Arrives next day


24h 5m • 2 changes
Arrives +2 days


32h 50m • 2 changes
Want to know about travelling from Oklahoma City to Lafayette? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Oklahoma City to Lafayette. However, there are services departing from Oklahoma City station and arriving at Lafayette station via St Louis Bus Station station. The journey, including transfers, takes approximately 27h 47m.
Oklahoma City to Lafayette bus services, operated by Greyhound USA, depart from Oklahoma City Bus Station.
Oklahoma City to Lafayette bus services, operated by Greyhound USA, arrive at Lafayette Amtrak Station.
Book your Oklahoma City to Lafayette bus tickets online with Greyhound USA and Amtrak Thruway.
The distance between Oklahoma City and Lafayette is 1,082.2 km. The road distance is 1,303 km.
You can take a bus from Oklahoma City Bus Station to Lafayette Amtrak Station via St Louis Bus Station and Indianapolis Union Station in around 17h 10m.