The average bus between Old Lyme and Portland takes 15h 43m and the fastest bus takes 7h 35m. The bus service runs several times per day from Old Lyme to Portland. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Old Lyme and Portland. The earliest departure is at 12:34 PM in the afternoon, and the last departure from Old Lyme is at 6:34 PM which arrives into Portland at 2:10 PM. All services require a transfer at Old Saybrook Train Station Bus Shelter and take an average of 15h 43m. The schedules shown below are for the next available departures.



10h 10m • 3 changes
Arrives next day



8h 50m • 3 changes
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19h 35m • 3 changes



10h 10m • 3 changes
Arrives next day



8h 50m • 3 changes
Arrives next day



19h 35m • 3 changes



10h 10m • 3 changes
Arrives next day



8h 50m • 3 changes
Arrives next day



19h 35m • 3 changes
Want to know about travelling from Old Lyme to Portland? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Old Lyme to Portland. However, there are services departing from Old Lyme station and arriving at Portland station via Asylum St @ Union Pl. The journey, including transfers, takes approximately 15h 43m.
Old Lyme to Portland bus services, operated by River Valley Transit, depart from Old Saybrook Trans Cntr station.
Old Lyme to Portland bus services, operated by River Valley Transit, arrive at Portland, ME station.
The distance between Old Lyme and Portland is 310.8 km. The road distance is 407 km.
You can take a bus from Lyme St & Library Ln to Portland, ME via Old Saybrook Train Station Bus Shelter, Old Saybrook Trans Cntr, Asylum St @ Union Pl, Hartford Union Station, South Station, and Boston, MA - South Station in around 7h 27m.