The average bus between Old Lyme and Syracuse takes 19h 40m and the fastest bus takes 10h 10m. There is at least one bus per day from Old Lyme to Syracuse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Old Lyme and Syracuse. The earliest departure is at 12:34 PM in the afternoon, and the last departure from Old Lyme is at 6:34 PM which arrives into Syracuse at 1:40 PM. All services require a transfer at Old Saybrook Train Station Bus Shelter and take an average of 19h 40m. The schedules shown below are for the next available departures.



10h 10m • 3 changes
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21h 5m • 3 changes
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24h 20m • 3 changes
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21h 5m • 3 changes
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24h 20m • 3 changes
Want to know about travelling from Old Lyme to Syracuse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Old Lyme to Syracuse. However, there are services departing from Old Lyme station and arriving at Syracuse station via Asylum St @ Union Pl. The journey, including transfers, takes approximately 19h 40m.
Old Lyme to Syracuse bus services, operated by River Valley Transit, depart from Old Saybrook Trans Cntr station.
Old Lyme to Syracuse bus services, operated by River Valley Transit, arrive at Syracuse Bus Station.
The distance between Old Lyme and Syracuse is 368.8 km. The road distance is 486 km.
You can take a bus from Lyme St & Library Ln to Syracuse Bus Station via Old Saybrook Train Station Bus Shelter, Old Saybrook Trans Cntr, Asylum St @ Union Pl, Hartford, Springfield, and Springfield Union Station in around 9h 33m.