The average bus between Old Town San Diego and San Ysidro takes 1h 25m and the fastest bus takes 36 min. The bus service runs several times per day from Old Town San Diego to San Ysidro. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Old Town San Diego and San Ysidro. The earliest departure is at 12:01 AM at night, and the last departure from Old Town San Diego is at 6:15 PM which arrives into San Ysidro at 6:59 PM. All services require a transfer, and take on average 1h 25m. The schedules shown below are for the next available departures.

3h 55m • 1 change

48 min • 1 change

55 min • 1 change

36 min • 1 change

3h 55m • 1 change

48 min • 1 change

55 min • 1 change

36 min • 1 change

3h 55m • 1 change

48 min • 1 change

55 min • 1 change

36 min • 1 change

4h 10m • 1 change

46 min • 1 change

51 min • 1 change

46 min • 1 change

5h 5m • 1 change

46 min • 1 change

51 min • 1 change

46 min • 1 change

3h 55m • 1 change

48 min • 1 change

55 min • 1 change

36 min • 1 change
Want to know about travelling from Old Town San Diego to San Ysidro? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Old Town San Diego to San Ysidro. However, there are services departing from Old Town San Diego station and arriving at San Ysidro station via San Ysidro Bus Terminal. The journey, including transfers, takes approximately 1h 25m.
Old Town San Diego to San Ysidro bus services, operated by Greyhound USA, depart from San Diego Greyhound Bus Stop station.
Old Town San Diego to San Ysidro bus services, operated by Greyhound USA, arrive at San Ysidro Bl & I-805 station.
The distance between Old Town San Diego and San Ysidro is 26.9 km. The road distance is 33 km.
You can take a bus from San Diego Greyhound Bus Stop to San Ysidro Bl & I-805 via San Ysidro Transit Center in around 37 min.