The average bus between Ontario and La Mesa takes 8h 24m and the fastest bus takes 6h 16m. The bus service runs several times per day from Ontario to La Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Ontario and La Mesa. The earliest departure is at 6:41 AM in the morning, and the last departure from Ontario is at 7:32 PM which arrives into La Mesa at 6:51 AM. All services require a transfer at Fontana Metrolink Transit Center and take an average of 8h 24m. The schedules shown below are for the next available departures.





6h 36m • 5 changes





6h 54m • 5 changes





6h 36m • 5 changes





6h 54m • 5 changes





6h 36m • 5 changes





6h 54m • 5 changes
Want to know about travelling from Ontario to La Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Ontario to La Mesa. However, there are services departing from Ontario station and arriving at La Mesa station via San Diego. The journey, including transfers, takes approximately 8h 24m.
Ontario to La Mesa bus services, operated by Omnitrans, depart from San Bernardino Downtown Transit Center station.
Ontario to La Mesa bus services, operated by Omnitrans, arrive at San Diego station.
The distance between Ontario and La Mesa is 155.4 km. The road distance is 241 km.
Flixbus USA operates a bus from San Bernardino Downtown Transit Center to San Diego twice daily. Tickets cost $17–30 and the journey takes 3h 20m.