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Orange County to Otay Mesa buses

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Trip Overview

The average bus between Orange County and Otay Mesa takes 4h 47m and the fastest bus takes 3h 19m. The bus service runs several times per day from Orange County to Otay Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 47m
Duration
112 mi
Distance
$39
Average price
3 times a day
Frequency

Bus (Greyhound)

best
  1. Take the bus from Santa Ana to San Ysidrobus bus Los Angeles
3h 5m
$25–43

Orange County to Otay Mesa bus times

Buses run 3 times a day between Orange County and Otay Mesa. The earliest departure is at 7:35 AM in the morning, and the last departure from Orange County is at 10:00 PM which arrives into Otay Mesa at 6:10 AM. All services require a transfer at San Ysidro and take an average of 4h 47m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from Orange County to Otay Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Orange County to Otay Mesa.ExpandLaunch map view
  • Distance: 112.1 mi
  • Duration: 4h 47m

What companies run services between Orange County, CA, USA and Otay Mesa, CA, USA?

Greyhound Mexico operates a bus from Santa Ana to San Ysidro 3 times a day. Tickets cost $21–35 and the journey takes 2h 20m.

Operators