The average bus between Orihuela and Madrid takes 7h 6m and the fastest bus takes 5h 50m. The bus service runs several times per day from Orihuela to Madrid. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Orihuela and Madrid. The earliest departure is at 7:45 AM in the morning, and the last departure from Orihuela is at 7:45 PM which arrives into Madrid at 4:50 AM. All services require a transfer, and take on average 7h 6m. The schedules shown below are for the next available departures.

6h 25m • 1 change

5h 50m • 1 change
Arrives next day

9h 5m • 1 change

6h 25m • 1 change

5h 50m • 1 change
Arrives next day

9h 5m • 1 change

6h 25m • 1 change

5h 50m • 1 change
Arrives next day

9h 5m • 1 change

6h 25m • 1 change

5h 50m • 1 change
Arrives next day

9h 5m • 1 change
Want to know about travelling from Orihuela to Madrid? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Orihuela to Madrid. However, there are services departing from Orihuela station and arriving at Madrid station via Estación Sur de Autobuses. The journey, including transfers, takes approximately 7h 6m.
Orihuela to Madrid bus services, operated by BusbamSL, depart from Estación de Autobuses de Murcia station.
Orihuela to Madrid bus services, operated by BusbamSL, arrive at Estación Sur de Autobuses station.
The distance between Orihuela and Madrid is 351.6 km. The road distance is 424 km.
ALSA operates a bus from Estación de Autobuses de Murcia to Estación Sur de Autobuses every 4 hours. Tickets cost €30–50 and the journey takes 4h 35m.