The average bus between Orihuela and Santander takes 16h 47m and the fastest bus takes 14h 30m. The bus service runs several times per day from Orihuela to Santander. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Orihuela and Santander. The earliest departure is at 7:45 AM in the morning, and the last departure from Orihuela is at 7:45 PM which arrives into Santander at 4:15 PM. All services require a transfer at Estación de Autobuses de Murcia and take an average of 16h 47m. The schedules shown below are for the next available departures.


14h 30m • 2 changes
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15h 45m • 2 changes
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20h 30m • 2 changes


14h 30m • 2 changes
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15h 45m • 2 changes
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20h 30m • 2 changes


14h 30m • 2 changes
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15h 45m • 2 changes
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20h 30m • 2 changes


14h 30m • 2 changes
Arrives next day


15h 45m • 2 changes
Arrives next day


20h 30m • 2 changes


14h 30m • 2 changes
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15h 45m • 2 changes
Arrives next day


20h 30m • 2 changes
Want to know about travelling from Orihuela to Santander? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Orihuela to Santander. However, there are services departing from Orihuela station and arriving at Santander station via Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid). The journey, including transfers, takes approximately 16h 47m.
Orihuela to Santander bus services, operated by ALSA, depart from Estación de Autobuses de Murcia station.
Orihuela to Santander bus services, operated by ALSA, arrive at Estación de autobuses de Santander station.
The distance between Orihuela and Santander is 644.8 km. The road distance is 835 km.
You can take a bus from Orihuela to Estación de autobuses de Santander via Estación de Autobuses de Murcia and Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) in around 13h 5m.