The average bus between Orlando and Des Moines takes 35h 4m and the fastest bus takes 34h. There is at least one bus per day from Orlando to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Orlando and Des Moines. The earliest departure is at 12:30 PM in the afternoon, and the last departure from Orlando is at 2:45 PM which arrives into Des Moines at 11:45 PM. All services require a transfer at Atlanta Bus Station and take an average of 35h 4m. The schedules shown below are for the next available departures.
Want to know about travelling from Orlando to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Orlando to Des Moines. However, there are services departing from Orlando station and arriving at Des Moines station via Atlanta Bus Station station. The journey, including transfers, takes approximately 35h 4m.
Orlando to Des Moines bus services, operated by Flixbus USA, depart from Orlando Bus Station.
Orlando to Des Moines bus services, operated by Flixbus USA, arrive at Des Moines station.
Book your Orlando to Des Moines bus tickets online with Flixbus USA and Greyhound USA.
The distance between Orlando and Des Moines is 1,825.8 km. The road distance is 2,277 km.
You can take a bus from Orlando Bus Station to Des Moines via Atlanta Bus Station and St Louis Bus Station in around 29h 20m.
