The bus between Orlando and Lake City takes 3h 45m. There is at least one bus per day from Orlando to Lake City. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Orlando and Lake City. The service departs Orlando at 5:15 AM in the morning, which arrives into Lake City at 09:00:00. All services run direct with no transfers required, and take on average 3h 45m. The schedules shown below are for the next available departures.
Want to know about travelling from Orlando to Lake City? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Orlando Bus Station and arriving at Lake City Bus Station. Services depart once daily, and operate every day. The journey takes approximately 3h 45m.
Orlando to Lake City bus services, operated by Greyhound USA, depart from Orlando Bus Station.
Orlando to Lake City bus services, operated by Greyhound USA, arrive at Lake City Bus Station.
Book your Orlando to Lake City bus tickets online with Omio and FlixBus.
The distance between Orlando and Lake City is 220.5 km. The road distance is 247 km.
Greyhound USA operates a bus from Orlando Bus Station to Lake City Bus Station once daily. Tickets cost $27–40 and the journey takes 3h 45m.