Rome2Rio

Orlando to Louisville, KY buses

Find Transport to Louisville, KY

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Trip Overview

The average bus between Orlando and Louisville, KY takes 18h 52m and the fastest bus takes 17h 30m. The bus service runs several times per day from Orlando to Louisville, KY. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

18h 52m
Duration
859 mi
Distance
$180
Average price
5 times a day
Frequency

Bus

best
  1. Take the bus from Orlando Bus Station to Atlanta Bus Stationbus bus FlixBus N2401 / ...
  2. Take the bus from Atlanta Bus Station to Louisville Bus Stationbus bus Greyhound US0105 / ...
17h 25m
$132–223

Orlando to Louisville, KY bus times

Buses run 5 times a day between Orlando and Louisville, KY. The earliest departure is at 12:55 AM at night, and the last departure from Orlando is at 8:50 PM which arrives into Louisville, KY at 2:20 PM. All services require a transfer, and take on average 18h 52m. The schedules shown below are for the next available departures.

Departing Saturday, October 24, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA19h 40m • 1 change

  •  → 

    Arrives next day

    Flixbus USAFlixbus USA19h 5m • 1 change

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA18h 55m • 1 change

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA17h 30m • 1 change

Departing Sunday, October 25, 2026

  •  → 

    Flixbus USAFlixbus USA18h 55m • 1 change

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA19h 40m • 1 change

  •  → 

    Arrives next day

    Flixbus USAFlixbus USA19h 5m • 1 change

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA18h 55m • 1 change
  • Show more

Departing Monday, October 26, 2026

  •  → 

    Flixbus USAFlixbus USA18h 55m • 1 change

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA19h 40m • 1 change

  •  → 

    Arrives next day

    Flixbus USAFlixbus USA19h 5m • 1 change

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA18h 55m • 1 change
  • Show more

Departing Tuesday, October 27, 2026

  •  → 

    Flixbus USAFlixbus USA18h 55m • 1 change

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA19h 40m • 1 change

  •  → 

    Arrives next day

    Flixbus USAFlixbus USA19h 5m • 1 change

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA18h 55m • 1 change
  • Show more

Departing Wednesday, October 28, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA19h 40m • 1 change

  •  → 

    Arrives next day

    Flixbus USAFlixbus USA19h 5m • 1 change

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA18h 55m • 1 change

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA17h 30m • 1 change

Departing Thursday, October 29, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA19h 40m • 1 change

  •  → 

    Arrives next day

    Flixbus USAFlixbus USA19h 5m • 1 change

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA21h 10m • 1 change

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA17h 30m • 1 change

Departing Friday, October 30, 2026

  •  → 

    Flixbus USAFlixbus USA18h 55m • 1 change

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA19h 40m • 1 change

Frequently asked questions

Want to know about travelling from Orlando to Louisville, KY? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Orlando to Louisville, KY.ExpandLaunch map view
  • Distance: 858.7 mi
  • Duration: 18h 52m

What companies run services between Orlando, FL, USA and Louisville, KY, USA?

You can take a bus from Orlando Bus Station to Louisville Bus Station via Atlanta Bus Station in around 17h 25m.

Operators