The bus between Orlando and Santa Cruz takes 3d. There is at least one bus per day from Orlando to Santa Cruz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Orlando and Santa Cruz. The earliest departure is at 9:30 AM in the morning, and the last departure from Orlando is at 8:50 PM which arrives into Santa Cruz at 6:17 PM. All services require a transfer at Atlanta Bus Station and take an average of 3d. The schedules shown below are for the next available departures.
Arrives +3 days




2d 23h • 4 changes
Arrives +3 days




2d 21h • 4 changes
Arrives +3 days




2d 21h • 4 changes
Arrives +3 days




2d 21h • 4 changes
Want to know about travelling from Orlando to Santa Cruz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Orlando to Santa Cruz. However, there are services departing from Orlando station and arriving at Santa Cruz station via Atlanta Bus Station station. The journey, including transfers, takes approximately 3d.
Orlando to Santa Cruz bus services, operated by Flixbus USA, depart from Orlando Bus Station.
Orlando to Santa Cruz bus services, operated by Flixbus USA, arrive at Soquel Ave & Front station.
The distance between Orlando and Santa Cruz is 3,884.4 km. The road distance is 4,931 km.
You can take a bus from Orlando Bus Station to Soquel Ave & Front via Atlanta Bus Station, Dallas Bus Station, Los Angeles Union Station, San Jose Diridon Station, and Diridon Station in around 2d 17h.