The average bus between Orleans and South Station takes 4h 58m and the fastest bus takes 2h 20m. The bus service runs several times per day from Orleans to South Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Orleans and South Station. The earliest departure is at 9:45 AM in the morning, and the last departure from Orleans is at 7:15 PM which arrives into South Station at 6:00 AM. All services require a transfer at Hyannis and take an average of 4h 58m. The schedules shown below are for the next available departures.

2h 20m • 1 change

2h 40m • 1 change
Arrives next day

10h 45m • 1 change

2h 20m • 1 change

2h 40m • 1 change
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10h 45m • 1 change

2h 20m • 1 change

2h 40m • 1 change
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10h 45m • 1 change

2h 20m • 1 change

2h 40m • 1 change
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10h 45m • 1 change

2h 20m • 1 change

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Arrives next day

10h 45m • 1 change
Want to know about travelling from Orleans to South Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Orleans to South Station. However, there are services departing from Orleans station and arriving at South Station station via Hyannis Transportation Center. The journey, including transfers, takes approximately 4h 58m.
Orleans to South Station bus services, operated by Peter Pan Bus Lines, depart from Orleans station.
Orleans to South Station bus services, operated by Peter Pan Bus Lines, arrive at Boston station.
The distance between Orleans and South Station is 107.9 km. The road distance is 148 km.
You can take a bus from Orleans to South Station via Hyannis and Boston in around 3h 11m.