Otay Mesa to Anaheim Buses

Otay Mesa to Anaheim buses

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Trip Overview

The average bus between Otay Mesa and Anaheim takes 5h 30m and the fastest bus takes 3h 27m. The bus service runs several times per day from Otay Mesa to Anaheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 30m
Duration: 119 mi
Distance: $32
Average price: Every 4 hours
Frequency

Bus, line 83 bus

best

Take the bus from San Ysidro to Santa Anabus Lxus 3126 / ...
Take the bus from Santa Ana-Santiago to Ball-Oxbus 83

4h 6m

$22–39

Otay Mesa to Anaheim bus times

Buses run every 4 hours between Otay Mesa and Anaheim. The earliest departure is at 5:01 AM in the morning, and the last departure from Otay Mesa is at 8:43 PM which arrives into Anaheim at 8:23 AM. All services require a transfer at Iris Avenue Transit Center and take an average of 5h 30m. The schedules shown below are for the next available departures.

Departing Friday, October 16, 2026

5:01 AM → 9:53 AM
4h 52m • 3 changes
8:48 AM → 1:27 PM
4h 39m • 3 changes
10:45 AM → 3:34 PM
4h 49m • 3 changes
4:30 PM → 7:57 PM
3h 27m • 3 changes
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Departing Saturday, October 17, 2026

8:28 AM → 1:31 PM
5h 3m • 3 changes
10:28 AM → 3:31 PM
5h 3m • 3 changes
4:28 PM → 7:56 PM
3h 28m • 3 changes
5:28 PM → 9:51 PM
4h 23m • 3 changes
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Departing Sunday, October 18, 2026

6:43 PM → 5:16 AM
Arrives next day
10h 33m • 3 changes
8:43 PM → 8:23 AM
Arrives next day
11h 40m • 3 changes

Departing Monday, October 19, 2026

5:01 AM → 9:53 AM
4h 52m • 3 changes
8:48 AM → 1:27 PM
4h 39m • 3 changes
10:45 AM → 3:34 PM
4h 49m • 3 changes
4:30 PM → 7:57 PM
3h 27m • 3 changes
Show more

Departing Tuesday, October 20, 2026

5:01 AM → 9:53 AM
4h 52m • 3 changes
8:48 AM → 1:27 PM
4h 39m • 3 changes
10:45 AM → 3:34 PM
4h 49m • 3 changes
4:30 PM → 7:57 PM
3h 27m • 3 changes
Show more

Departing Wednesday, October 21, 2026

5:01 AM → 9:53 AM
4h 52m • 3 changes
8:48 AM → 1:27 PM
4h 39m • 3 changes
10:45 AM → 3:34 PM
4h 49m • 3 changes
4:30 PM → 7:57 PM
3h 27m • 3 changes
Show more

Departing Thursday, October 22, 2026

5:01 AM → 9:53 AM
4h 52m • 3 changes
8:48 AM → 1:27 PM
4h 39m • 3 changes
10:45 AM → 3:34 PM
4h 49m • 3 changes
4:30 PM → 7:57 PM
3h 27m • 3 changes
Show more

Frequently asked questions

Want to know about travelling from Otay Mesa to Anaheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

What companies run services between Otay Mesa, CA, USA and Anaheim, CA, USA?

You can take a bus from Otay Mesa Rd & Cactus Rd to Ball-Ox via Iris Avenue Transit Center, San Ysidro Transit Center, San Ysidro, Santa Ana, and Santa Ana-Santiago in around 4h 6m.

Operators