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Otay Mesa to Los Angeles buses

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Trip Overview

The average bus between Otay Mesa and Los Angeles takes 4h 18m and the fastest bus takes 4h 2m. The bus service runs several times per day from Otay Mesa to Los Angeles. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 18m
Duration
143 mi
Distance
$75
Average price
3 times a day
Frequency

Otay Mesa to Los Angeles bus times

Buses run 3 times a day between Otay Mesa and Los Angeles. The earliest departure is at 5:29 AM in the morning, and the last departure from Otay Mesa is at 10:28 AM which arrives into Los Angeles at 2:30 PM. All services require a transfer at Iris Avenue Transit Center and take an average of 4h 18m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from Otay Mesa to Los Angeles? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Otay Mesa to Los Angeles.ExpandLaunch map view
  • Distance: 143.4 mi
  • Duration: 4h 18m

What companies run services between Otay Mesa, CA, USA and Los Angeles, CA, USA?

Tufesa operates a bus from San Ysidro, CA to Downtown Los Angeles 3 times a day. Tickets cost $40–65 and the journey takes 3h.

Operators