The average bus between Otay Mesa and Mexicali takes 5h 15m and the fastest bus takes 4h 39m. The bus service runs several times per day from Otay Mesa to Mexicali. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Otay Mesa and Mexicali. The earliest departure is at 5:01 AM in the morning, and the last departure from Otay Mesa is at 8:43 PM which arrives into Mexicali at 1:45 AM. All services require a transfer at Iris Avenue Transit Center and take an average of 5h 15m. The schedules shown below are for the next available departures.



5h 25m • 3 changes



5h 15m • 3 changes



4h 39m • 3 changes



4h 55m • 3 changes



5h 12m • 3 changes



6h 12m • 3 changes



5h 2m • 3 changes



5h 12m • 3 changes



5h 57m • 3 changes



5h 57m • 3 changes



5h 47m • 3 changes



4h 57m • 3 changes



5h 39m • 3 changes



5h 22m • 3 changes



5h 25m • 3 changes



5h 15m • 3 changes



5h 39m • 3 changes



5h 22m • 3 changes



5h 25m • 3 changes



5h 15m • 3 changes



5h 39m • 3 changes



5h 22m • 3 changes



5h 25m • 3 changes



5h 15m • 3 changes
Want to know about travelling from Otay Mesa to Mexicali? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Otay Mesa to Mexicali. However, there are services departing from Otay Mesa station and arriving at Mexicali station via Mexicali. The journey, including transfers, takes approximately 5h 15m.
Otay Mesa to Mexicali bus services, operated by San Diego Metro Transit, depart from Tijuana station.
Otay Mesa to Mexicali bus services, operated by San Diego Metro Transit, arrive at Mexicali station.
The distance between Otay Mesa and Mexicali is 143.8 km. The road distance is 189 km.
Autobuses ABC operates a bus from Tijuana to Mexicali every 3 hours. Tickets cost $360–650 and the journey takes 2h 5m.