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Otay Mesa to Ontario buses

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Trip Overview

The average bus between Otay Mesa and Ontario takes 10h 6m and the fastest bus takes 9h 30m. The bus runs, on average, 6 times per week from Otay Mesa to Ontario. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h 6m
Duration
166 mi
Distance
$58
Average price
6 times a week
Frequency

Otay Mesa to Ontario bus times

Buses run 6 times a week between Otay Mesa and Ontario. The earliest departure is at 6:28 PM in the evening, and the last departure from Otay Mesa is at 6:43 PM which arrives into Ontario at 4:13 AM. All services require a transfer at Iris Avenue Transit Center and take an average of 10h 6m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    San Diego Metro TransitSan Diego Metro TransitLimousine ExpressFoothill TransitOmnitrans9h 41m • 4 changes

Departing Wednesday, November 11, 2026

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    Arrives next day

    San Diego Metro TransitSan Diego Metro TransitLimousine ExpressFoothill TransitOmnitrans9h 41m • 4 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    San Diego Metro TransitSan Diego Metro TransitLimousine ExpressFoothill TransitOmnitrans9h 41m • 4 changes

Departing Friday, November 13, 2026

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    Arrives next day

    San Diego Metro TransitSan Diego Metro TransitLimousine ExpressFoothill TransitOmnitrans11h 9m • 4 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    San Diego Metro TransitSan Diego Metro TransitLimousine ExpressFoothill TransitOmnitrans10h 50m • 4 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    San Diego Metro TransitSan Diego Metro TransitLimousine ExpressFoothill TransitOmnitrans9h 30m • 4 changes

Frequently asked questions

Want to know about travelling from Otay Mesa to Ontario? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Otay Mesa to Ontario.ExpandLaunch map view
  • Distance: 166.1 mi
  • Duration: 10h 6m

What companies run services between Otay Mesa, CA, USA and Ontario, CA, USA?

You can take a bus from Otay Mesa Rd & Cactus Rd to Holt @ Palm via Iris Avenue Transit Center, San Ysidro Transit Center, San Ysidro, El Monte, Garvey Ave and Mountain View Rd E, and Pomona Transit Center in around 6h 8m.

Operators