The average bus between Otay Mesa and San Bernardino takes 5h 39m and the fastest bus takes 4h 42m. The bus service runs several times per day from Otay Mesa to San Bernardino. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Otay Mesa and San Bernardino. The earliest departure is at 5:29 AM in the morning, and the last departure from Otay Mesa is at 6:45 AM which arrives into San Bernardino at 1:20 PM. All services require a transfer at Iris Avenue Transit Center and take an average of 5h 39m. The schedules shown below are for the next available departures.
Want to know about travelling from Otay Mesa to San Bernardino? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Otay Mesa to San Bernardino. However, there are services departing from Otay Mesa station and arriving at San Bernardino station via San Bernardino Downtown Transit Center. The journey, including transfers, takes approximately 5h 39m.
Otay Mesa to San Bernardino bus services, operated by San Diego Metro Transit, depart from San Ysidro Bus Terminal station.
Otay Mesa to San Bernardino bus services, operated by San Diego Metro Transit, arrive at San Bernardino Downtown Transit Center station.
The distance between Otay Mesa and San Bernardino is 174.1 km. The road distance is 223 km.
Flixbus USA operates a bus from San Ysidro Bus Terminal to San Bernardino Downtown Transit Center twice daily. Tickets cost $20–35 and the journey takes 3h 30m.