Otay Mesa to Vista Buses

Otay Mesa to Vista buses

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Trip Overview

The average bus between Otay Mesa and Vista takes 3h 59m and the fastest bus takes 3h 11m. There is an hourly bus service from Otay Mesa to Vista. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 59m
Duration: 78 mi
Distance: $20
Average price: Hourly
Frequency

Line 225 bus, bus, line 305 bus

best

Take the bus from Otay Mesa Transit Center to Broadway & Park Blbus 225
Take the bus from Broadway & Park Bl to Escondido Transit Centerbus 235
Take the bus from Escondido Transit Center Stall 6 to S Santa Fe Av & Broadwaybus 305

3h 53m

$8–20

Otay Mesa to Vista bus times

Buses run hourly between Otay Mesa and Vista. The earliest departure is at 5:03 AM in the morning, and the last departure from Otay Mesa is at 9:48 PM which arrives into Vista at 7:26 AM. All services require a transfer at Otay Mesa Transit Center and take an average of 3h 59m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

8:41 AM → 12:20 PM
3h 39m • 3 changes
9:19 AM → 12:50 PM
3h 31m • 3 changes
9:49 AM → 1:22 PM
3h 33m • 3 changes
10:19 AM → 1:52 PM
3h 33m • 3 changes
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Departing Thursday, November 5, 2026

5:03 AM → 8:57 AM
3h 54m • 3 changes
5:33 AM → 9:24 AM
3h 51m • 3 changes
6:04 AM → 9:52 AM
3h 48m • 3 changes
6:20 AM → 10:22 AM
4h 2m • 3 changes
Show more

Departing Friday, November 6, 2026

5:03 AM → 8:57 AM
3h 54m • 3 changes
5:33 AM → 9:24 AM
3h 51m • 3 changes
6:04 AM → 9:52 AM
3h 48m • 3 changes
6:20 AM → 10:22 AM
4h 2m • 3 changes
Show more

Departing Saturday, November 7, 2026

5:55 AM → 9:26 AM
3h 31m • 3 changes
6:54 AM → 10:21 AM
3h 27m • 3 changes
7:54 AM → 11:21 AM
3h 27m • 3 changes
8:54 AM → 12:21 PM
3h 27m • 3 changes
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Departing Sunday, November 8, 2026

6:10 AM → 9:51 AM
3h 41m • 3 changes
7:09 AM → 10:51 AM
3h 42m • 3 changes
8:09 AM → 11:51 AM
3h 42m • 3 changes
9:09 AM → 12:51 PM
3h 42m • 3 changes
Show more

Departing Monday, November 9, 2026

5:03 AM → 8:57 AM
3h 54m • 3 changes
5:33 AM → 9:24 AM
3h 51m • 3 changes
6:04 AM → 9:52 AM
3h 48m • 3 changes
6:20 AM → 10:22 AM
4h 2m • 3 changes
Show more

Departing Tuesday, November 10, 2026

5:03 AM → 8:57 AM
3h 54m • 3 changes
5:33 AM → 9:24 AM
3h 51m • 3 changes
6:04 AM → 9:52 AM
3h 48m • 3 changes
6:20 AM → 10:22 AM
4h 2m • 3 changes
Show more

Frequently asked questions

Want to know about travelling from Otay Mesa to Vista? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Find Transport to Vista

Trip Overview

Line 225 bus, bus, line 305 bus

Otay Mesa to Vista bus times

Departing Wednesday, November 4, 2026

8:41 AM → 12:20 PM

9:19 AM → 12:50 PM

9:49 AM → 1:22 PM

10:19 AM → 1:52 PM

Departing Thursday, November 5, 2026

5:03 AM → 8:57 AM

5:33 AM → 9:24 AM

6:04 AM → 9:52 AM

6:20 AM → 10:22 AM

Departing Friday, November 6, 2026

5:03 AM → 8:57 AM

5:33 AM → 9:24 AM

6:04 AM → 9:52 AM

6:20 AM → 10:22 AM

Departing Saturday, November 7, 2026

5:55 AM → 9:26 AM

6:54 AM → 10:21 AM

7:54 AM → 11:21 AM

8:54 AM → 12:21 PM

Departing Sunday, November 8, 2026

6:10 AM → 9:51 AM

7:09 AM → 10:51 AM

8:09 AM → 11:51 AM

9:09 AM → 12:51 PM

Departing Monday, November 9, 2026

5:03 AM → 8:57 AM

5:33 AM → 9:24 AM

6:04 AM → 9:52 AM

6:20 AM → 10:22 AM

Departing Tuesday, November 10, 2026

5:03 AM → 8:57 AM

5:33 AM → 9:24 AM

6:04 AM → 9:52 AM

6:20 AM → 10:22 AM

Frequently asked questions

What companies run services between Otay Mesa, CA, USA and Vista, CA, USA?

Bus from Otay Mesa Transit Center to Broadway & Park Bl

Bus from Broadway & Park Bl to Escondido Transit Center

Bus from Escondido Transit Center Stall 6 to S Santa Fe Av & Broadway

Bus trips from Otay Mesa

Bus trips to Vista

Alternative transport options