The average bus between Otogar (Istanbul Metro) and Eskişehir takes 6h 5m and the fastest bus takes 5h 30m. The bus service runs several times per day from Otogar (Istanbul Metro) to Eskişehir. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Otogar (Istanbul Metro) and Eskişehir. The earliest departure is at 3:00 AM at night, and the last departure from Otogar (Istanbul Metro) is at 3:00 PM which arrives into Eskişehir at 9:00 PM. All services require a transfer at Bursa and take an average of 6h 5m. The schedules shown below are for the next available departures.

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Want to know about travelling from Otogar (Istanbul Metro) to Eskişehir? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Otogar (Istanbul Metro) to Eskişehir. However, there are services departing from Otogar (Istanbul Metro) station and arriving at Eskişehir station via Bursa. The journey, including transfers, takes approximately 6h 5m.
Otogar (Istanbul Metro) to Eskişehir bus services, operated by Kale Seyahat, depart from Esenler Otogar station.
Otogar (Istanbul Metro) to Eskişehir bus services, operated by Kale Seyahat, arrive at Eskişehir TCDD train station.
Book your Otogar (Istanbul Metro) to Eskişehir bus tickets online with Kale Seyahat, Kamil Koç and Pamukkale Turizm.
The distance between Otogar (Istanbul Metro) and Eskişehir is 196.6 km. The road distance is 315 km.
You can take a bus from Esenler Otogar to Eskişehir TCDD train station via Bursa and Bursa bus station in around 4h 51m.