The average bus between Otranto and Florence takes 14h 52m and the fastest bus takes 14h 5m. The bus service runs several times per day from Otranto to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Otranto and Florence. The earliest departure is at 7:10 AM in the morning, and the last departure from Otranto is at 6:48 PM which arrives into Florence at 10:15 AM. All services require a transfer at Lecce and take an average of 14h 52m. The schedules shown below are for the next available departures.


14h 5m • 2 changes
Arrives next day


15h 10m • 2 changes
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15h 27m • 2 changes


14h 5m • 2 changes
Arrives next day


15h 10m • 2 changes
Arrives next day


15h 27m • 2 changes


14h 5m • 2 changes
Arrives next day


15h 10m • 2 changes
Arrives next day


15h 27m • 2 changes


14h 5m • 2 changes
Arrives next day


15h 10m • 2 changes
Arrives next day


15h 27m • 2 changes
Want to know about travelling from Otranto to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Otranto to Florence. However, there are services departing from Otranto station and arriving at Florence station via Lecce - City Terminal. The journey, including transfers, takes approximately 14h 52m.
Otranto to Florence bus services, operated by Salento in bus, depart from Otranto - Stazione FSE station.
Otranto to Florence bus services, operated by Salento in bus, arrive at Florence Villa Constanza Bus Station.
Book your Otranto to Florence bus tickets online with Salento in bus, FlixBus and Itabus S.p.A..
The distance between Otranto and Florence is 721.6 km. The road distance is 939 km.
You can take a bus from Otranto - Stazione FSE to Florence Villa Constanza Bus Station via Lecce and Roma, Autostazione Tiburtina in around 14h 38m.