The average bus between Otranto and Melpignano takes 1h 38m and the fastest bus takes 50 min. The bus service runs several times per day from Otranto to Melpignano. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Otranto and Melpignano. The earliest departure is at 7:10 AM in the morning, and the last departure from Otranto is at 7:00 PM which arrives into Melpignano at 8:36 PM. All services require a transfer, and take on average 1h 38m. The schedules shown below are for the next available departures.

1h 25m • 1 change

2h 35m • 1 change

1h 24m • 1 change

50 min • 1 change

1h 25m • 1 change

2h 35m • 1 change

1h 24m • 1 change

50 min • 1 change

1h 25m • 1 change

2h 35m • 1 change

1h 24m • 1 change

50 min • 1 change

1h 25m • 1 change

2h 35m • 1 change

1h 24m • 1 change

50 min • 1 change

1h 25m • 1 change

2h 35m • 1 change

1h 24m • 1 change

50 min • 1 change
Want to know about travelling from Otranto to Melpignano? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Otranto to Melpignano. However, there are services departing from Otranto station and arriving at Melpignano station via Maglie - Stazione FSE. The journey, including transfers, takes approximately 1h 38m.
Otranto to Melpignano bus services, operated by Salento in bus, depart from Otranto - Stazione FSE station.
Otranto to Melpignano bus services, operated by Salento in bus, arrive at Melpignano station.
The distance between Otranto and Melpignano is 16.4 km. The road distance is 22 km.
You can take a bus from Otranto - Stazione FSE to Melpignano via Maglie in around 1h 35m.