The average bus between Paddington and Manchester takes 5h 35m and the fastest bus takes 4h 50m. The bus service runs several times per day from Paddington to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Paddington and Manchester. The earliest departure is at 8:55 AM in the morning, and the last departure from Paddington is at 10:16 PM which arrives into Manchester at 6:15 AM. All services require a transfer, and take on average 5h 35m. The schedules shown below are for the next available departures.

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Arrives next day

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Want to know about travelling from Paddington to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Paddington to Manchester. However, there are services departing from Paddington station and arriving at Manchester station via Manchester Central Coach Station station. The journey, including transfers, takes approximately 5h 35m.
Paddington to Manchester bus services, operated by National Express, depart from Golders Green Station.
Paddington to Manchester bus services, operated by National Express, arrive at Manchester Central Coach Station.
Book your Paddington to Manchester bus tickets online with National Express.
The distance between Paddington and Manchester is 259.1 km. The road distance is 302 km.
National Express operates a bus from Golders Green Station to Manchester Central Coach Station hourly. Tickets cost £30–85 and the journey takes 4h 15m.