Paddington to Manchester Piccadilly Station bus times
Buses run 3 times a day between Paddington and Manchester Piccadilly Station. The earliest departure is at 10:37 AM in the morning, and the last departure from Paddington is at 9:06 PM which arrives into Manchester Piccadilly Station at 2:00 AM. All services require a transfer at Finchley Road / O2 Centre and take an average of 5h 14m. The schedules shown below are for the next available departures.
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5h 23m • 1 change
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5h 18m • 1 change
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Arrives next day
5h 11m • 1 change
Departing Wednesday, August 19, 2026
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5h 23m • 1 change
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5h 18m • 1 change
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Arrives next day
5h 11m • 1 change
Departing Thursday, August 20, 2026
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5h 23m • 1 change
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5h 18m • 1 change
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Arrives next day
5h 11m • 1 change
Departing Friday, August 21, 2026
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5h 20m • 1 change
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5h 16m • 1 change
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Arrives next day
4h 54m • 1 change
Departing Saturday, August 22, 2026
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5h 18m • 1 change
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5h 8m • 1 change
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Arrives next day
4h 58m • 1 change
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