The average bus between Palatine and St. Louis takes 10h 15m and the fastest bus takes 7h 52m. The bus service runs several times per day from Palatine to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Palatine and St. Louis. The earliest departure is at 5:51 AM in the morning, and the last departure from Palatine is at 8:48 PM which arrives into St. Louis at 3:40 PM. All services require a transfer at Northwest Transportation Center and take an average of 10h 15m. The schedules shown below are for the next available departures.


7h 52m • 2 changes
Arrives next day


10h 57m • 2 changes
Arrives next day


18h 52m • 2 changes


9h 49m • 2 changes


8h 13m • 2 changes
Arrives next day


11h 8m • 2 changes


9h 49m • 2 changes


8h 13m • 2 changes
Arrives next day


11h 8m • 2 changes


9h 49m • 2 changes


8h 13m • 2 changes
Arrives next day


11h 8m • 2 changes
Want to know about travelling from Palatine to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Palatine to St. Louis. However, there are services departing from Palatine station and arriving at St. Louis station via Illinois Terminal. The journey, including transfers, takes approximately 10h 15m.
Palatine to St. Louis bus services, operated by Pace Bus, depart from Woodfield Mall station.
Palatine to St. Louis bus services, operated by Pace Bus, arrive at St Louis Bus Station.
The distance between Palatine and St. Louis is 428.4 km. The road distance is 550 km.
You can take a bus from Rand/Evergreen to St Louis Bus Station via Northwest Transportation Center, Woodfield Mall, Illinois Terminal, and Champaign Intermodal Trans Ctr in around 9h 9m.