The bus between Palermo and Brindisi takes 11h 45m. The bus runs, on average, once a week from Palermo to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once a week between Palermo and Brindisi. The service departs Palermo at 6:15 PM in the evening, which arrives into Brindisi at 06:00:00. All services run direct with no transfers required, and take on average 11h 45m. The schedules shown below are for the next available departures.
Want to know about travelling from Palermo to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Palermo station and arriving at Brindisi station. Services depart once a week, and operate Once daily. The journey takes approximately 11h 45m.
Palermo to Brindisi bus services, operated by FlixBus, depart from Palermo station.
Palermo to Brindisi bus services, operated by FlixBus, arrive at Brindisi station.
Book your Palermo to Brindisi bus tickets online with FlixBus.
The distance between Palermo and Brindisi is 483.2 km. The road distance is 753 km.
FlixBus operates a bus from Palermo to Brindisi once daily. Tickets cost €55–95 and the journey takes 11h 45m.