The average bus between Palermo and Cassibile takes 6h 52m and the fastest bus takes 4h. The bus service runs several times per day from Palermo to Cassibile. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Palermo and Cassibile. The earliest departure is at 8:00 AM in the morning, and the last departure from Palermo is at 5:00 PM which arrives into Cassibile at 7:30 AM. All services require a transfer at Siracusa Bus Terminal and take an average of 6h 52m. The schedules shown below are for the next available departures.

5h • 1 change

4h • 1 change

4h • 1 change
Arrives next day

14h 30m • 1 change

5h • 1 change

4h • 1 change

4h • 1 change
Arrives next day

14h 30m • 1 change

5h • 1 change

4h • 1 change

4h • 1 change
Arrives next day

14h 30m • 1 change

5h • 1 change

4h • 1 change

4h • 1 change
Arrives next day

14h 30m • 1 change
Want to know about travelling from Palermo to Cassibile? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Palermo to Cassibile. However, there are services departing from Palermo station and arriving at Cassibile station via Siracusa Bus Terminal. The journey, including transfers, takes approximately 6h 52m.
Palermo to Cassibile bus services, operated by Interbus, depart from Palermo station.
Palermo to Cassibile bus services, operated by Interbus, arrive at Siracusa Bus Terminal station.
The distance between Palermo and Cassibile is 208.5 km. The road distance is 273 km.
Interbus operates a bus from Palermo station to Siracusa Bus Terminal 4 times a day. Tickets cost €13–35 and the journey takes 3h 25m.