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Palo Alto to Irvine buses

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Trip Overview

The average bus between Palo Alto and Irvine takes 12h 19m and the fastest bus takes 10h 29m. There is at least one bus per day from Palo Alto to Irvine. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 19m
Duration
415 mi
Distance
$59
Average price
Once daily
Frequency

Palo Alto to Irvine bus times

Buses run once daily between Palo Alto and Irvine. The earliest departure is at 6:34 AM in the morning, and the last departure from Palo Alto is at 6:50 AM which arrives into Irvine at 5:47 AM. All services require a transfer at Tully & King and take an average of 12h 19m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Santa Clara VTAHoang ExpressOCTAOCTA10h 29m • 3 changes

Departing Thursday, November 12, 2026

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    Santa Clara VTAHoang ExpressOCTAOCTA10h 29m • 3 changes

Departing Friday, November 13, 2026

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    Santa Clara VTAHoang ExpressOCTAOCTA10h 29m • 3 changes

Departing Saturday, November 14, 2026

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    Santa Clara VTAHoang ExpressOCTAOCTA10h 49m • 3 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    Santa Clara VTAHoang ExpressOCTAOCTA22h 56m • 3 changes

Departing Monday, November 16, 2026

  •  → 

    Santa Clara VTAHoang ExpressOCTAOCTA10h 29m • 3 changes

Departing Tuesday, November 17, 2026

  •  → 

    Santa Clara VTAHoang ExpressOCTAOCTA10h 29m • 3 changes

Frequently asked questions

Want to know about travelling from Palo Alto to Irvine? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Palo Alto to Irvine.ExpandLaunch map view
  • Distance: 415 mi
  • Duration: 12h 19m

What companies run services between Palo Alto, CA, USA and Irvine, CA, USA?

Hoang Express operates a bus from San Jose, CA - Huong Lan Sandwich to Westminster, CA - ABC Supermarket once daily. Tickets cost $45–60 and the journey takes 6h 30m. Xe Do Hoang Transportation also services this route once daily.

Operators