Palo Alto to Milpitas Buses

Palo Alto to Milpitas buses

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Trip Overview

The average bus between Palo Alto and Milpitas takes 2h 6m and the fastest bus takes 1h 24m. The bus runs at least 2 times per hour from Palo Alto to Milpitas. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 6m
Duration: 26 mi
Distance: $10
Average price: Every 30 minutes
Frequency

Line 22 bus, line 66 bus

best

Take the bus from El Camino & California to Santa Clara & 2ndbus Rapid 522 / ...
Take the bus from 1st & Santa Clara to Main & Serrabus 66

2h 14m

$4–10

Palo Alto to Milpitas bus times

Buses run every 30 minutes between Palo Alto and Milpitas. The earliest departure is at 1:53 AM at night, and the last departure from Palo Alto is at 10:55 PM which arrives into Milpitas at 12:37 AM. All services require a transfer at Santa Clara & 2nd and take an average of 2h 6m. The schedules shown below are for the next available departures.

Departing Wednesday, October 21, 2026

5:02 PM → 7:25 PM
2h 23m • 1 change
5:19 PM → 7:38 PM
2h 19m • 1 change
5:36 PM → 7:50 PM
2h 14m • 1 change
5:57 PM → 8:18 PM
2h 21m • 1 change
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Departing Thursday, October 22, 2026

1:53 AM → 5:32 AM
3h 39m • 1 change
4:27 AM → 6:11 AM
1h 44m • 1 change
4:54 AM → 6:48 AM
1h 54m • 1 change
5:37 AM → 7:13 AM
1h 36m • 1 change
Show more

Departing Friday, October 23, 2026

1:53 AM → 5:32 AM
3h 39m • 1 change
4:27 AM → 6:11 AM
1h 44m • 1 change
4:54 AM → 6:48 AM
1h 54m • 1 change
5:37 AM → 7:13 AM
1h 36m • 1 change
Show more

Departing Saturday, October 24, 2026

4:40 AM → 6:04 AM
1h 24m • 1 change
5:07 AM → 6:36 AM
1h 29m • 1 change
5:32 AM → 7:06 AM
1h 34m • 1 change
6:08 AM → 7:55 AM
1h 47m • 1 change
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Departing Sunday, October 25, 2026

4:40 AM → 6:10 AM
1h 30m • 1 change
5:08 AM → 6:38 AM
1h 30m • 1 change
5:32 AM → 7:06 AM
1h 34m • 1 change
6:08 AM → 7:34 AM
1h 26m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Palo Alto to Milpitas? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Palo Alto to Milpitas buses

Trip Overview

Line 22 bus, line 66 bus

Palo Alto to Milpitas bus times

Departing Wednesday, October 21, 2026

5:02 PM → 7:25 PM

5:19 PM → 7:38 PM

5:36 PM → 7:50 PM

5:57 PM → 8:18 PM

Departing Thursday, October 22, 2026

1:53 AM → 5:32 AM

4:27 AM → 6:11 AM

4:54 AM → 6:48 AM

5:37 AM → 7:13 AM

Departing Friday, October 23, 2026

1:53 AM → 5:32 AM

4:27 AM → 6:11 AM

4:54 AM → 6:48 AM

5:37 AM → 7:13 AM

Departing Saturday, October 24, 2026

4:40 AM → 6:04 AM

5:07 AM → 6:36 AM

5:32 AM → 7:06 AM

6:08 AM → 7:55 AM

Departing Sunday, October 25, 2026

4:40 AM → 6:10 AM

5:08 AM → 6:38 AM

5:32 AM → 7:06 AM

6:08 AM → 7:34 AM

Frequently asked questions

What companies run services between Palo Alto, CA, USA and Milpitas, CA, USA?

Bus from El Camino & California to Santa Clara & 2nd

Bus from 1st & Santa Clara to Main & Serra

Palo Alto to Milpitas buses

Find Transport to Milpitas

Trip Overview

Line 22 bus, line 66 bus

Palo Alto to Milpitas bus times

Departing Wednesday, October 21, 2026

5:02 PM → 7:25 PM

5:19 PM → 7:38 PM

5:36 PM → 7:50 PM

5:57 PM → 8:18 PM

Departing Thursday, October 22, 2026

1:53 AM → 5:32 AM

4:27 AM → 6:11 AM

4:54 AM → 6:48 AM

5:37 AM → 7:13 AM

Departing Friday, October 23, 2026

1:53 AM → 5:32 AM

4:27 AM → 6:11 AM

4:54 AM → 6:48 AM

5:37 AM → 7:13 AM

Departing Saturday, October 24, 2026

4:40 AM → 6:04 AM

5:07 AM → 6:36 AM

5:32 AM → 7:06 AM

6:08 AM → 7:55 AM

Departing Sunday, October 25, 2026

4:40 AM → 6:10 AM

5:08 AM → 6:38 AM

5:32 AM → 7:06 AM

6:08 AM → 7:34 AM

Frequently asked questions

What companies run services between Palo Alto, CA, USA and Milpitas, CA, USA?

Bus from El Camino & California to Santa Clara & 2nd

Bus from 1st & Santa Clara to Main & Serra

Bus trips from Palo Alto

Bus trips to Milpitas

Alternative transport options