- Distance: 24 mi
- Duration: 57 min
The average bus between Palo Alto and South San Francisco takes 57 min and the fastest bus takes 56 min. The bus service runs several times per day from Palo Alto to South San Francisco. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Palo Alto and South San Francisco. The earliest departure is at 7:33 AM in the morning, and the last departure from Palo Alto is at 6:47 PM which arrives into South San Francisco at 7:43 PM. All services run direct with no transfers required, and take on average 57 min. The schedules shown below are for the next available departures.
Want to know about travelling from Palo Alto to South San Francisco? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Palo Alto station and arriving at South San Francisco station. Services depart every 3 hours, and operate 5 times a week. The journey takes approximately 57 min.
Palo Alto to South San Francisco bus services, operated by SamTrans, depart from E Bayshore Rd & Donohoe St station.
Palo Alto to South San Francisco bus services, operated by SamTrans, arrive at San Bruno BART-Bay 9 Outer Busway station.
The distance between Palo Alto and South San Francisco is 33.2 km. The road distance is 39 km.
SamTrans operates a bus from E Bayshore Rd & Donohoe St to San Bruno BART-Bay 9 Outer Busway hourly. Tickets cost $2–4 and the journey takes 56 min.