The average bus between Paoli and Hyannis takes 11h 43m and the fastest bus takes 11h 6m. The bus service runs several times per day from Paoli to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Paoli and Hyannis. The earliest departure is at 6:32 AM in the morning, and the last departure from Paoli is at 10:01 PM which arrives into Hyannis at 9:35 AM. All services require a transfer at Jefferson Station and take an average of 11h 43m. The schedules shown below are for the next available departures.




11h 13m • 4 changes




11h 6m • 4 changes
Arrives next day




12h 51m • 4 changes




11h 13m • 4 changes




11h 6m • 4 changes
Arrives next day




12h 51m • 4 changes
Want to know about travelling from Paoli to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Paoli to Hyannis. However, there are services departing from Paoli station and arriving at Hyannis station via Port Authority Bus Terminal. The journey, including transfers, takes approximately 11h 43m.
Paoli to Hyannis bus services, operated by SEPTA, depart from Philadelphia Bus Station.
Paoli to Hyannis bus services, operated by SEPTA, arrive at Hyannis Transportation Center station.
Book your Paoli to Hyannis bus tickets online with SEPTA, Flixbus USA and Peter Pan Bus Lines.
The distance between Paoli and Hyannis is 472.7 km. The road distance is 679 km.
You can take a train from Paoli to Hyannis Transportation Center via Jefferson Station, Philadelphia Bus Station, Port Authority Bus Terminal, and Providence Bus Terminal in around 11h 40m.