The average bus between Paoli and Niagara Falls takes 13h 48m and the fastest bus takes 12h 29m. The bus service runs several times per day from Paoli to Niagara Falls. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Paoli and Niagara Falls. The earliest departure is at 6:32 AM in the morning, and the last departure from Paoli is at 10:01 PM which arrives into Niagara Falls at 5:40 PM. All services require a transfer at Gray 30th St Station and take an average of 13h 48m. The schedules shown below are for the next available departures.
Arrives next day



14h 39m • 3 changes
Arrives next day



12h 46m • 3 changes



12h 58m • 3 changes
Arrives next day



13h 18m • 3 changes
Arrives next day



12h 46m • 3 changes
Want to know about travelling from Paoli to Niagara Falls? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Paoli to Niagara Falls. However, there are services departing from Paoli station and arriving at Niagara Falls station via Scranton. The journey, including transfers, takes approximately 13h 48m.
Paoli to Niagara Falls bus services, operated by SEPTA, depart from Philadelphia 30th St Station.
Paoli to Niagara Falls bus services, operated by SEPTA, arrive at Buffalo station.
Book your Paoli to Niagara Falls bus tickets online with SEPTA, Flixbus USA and Greyhound USA.
The distance between Paoli and Niagara Falls is 451.1 km. The road distance is 720 km.
You can take a train from Paoli to Main Street & Pine Avenue via Gray 30th St Station, Philadelphia 30th St Station, Scranton Bus Station, Buffalo, and Ellicott Street & MTC Static in around 12h 42m.