The average bus between Penn State Harrisburg and Manhattan takes 7h 12m and the fastest bus takes 5h 22m. The bus service runs several times per day from Penn State Harrisburg to Manhattan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Penn State Harrisburg and Manhattan. The earliest departure is at 10:03 AM in the morning, and the last departure from Penn State Harrisburg is at 8:33 PM which arrives into Manhattan at 6:40 AM. All services require a transfer at Penn State Harrisburg - Stop B and take an average of 7h 12m. The schedules shown below are for the next available departures.

5h 22m • 1 change

6h 2m • 1 change
Arrives next day

10h 7m • 1 change

5h 22m • 1 change

6h 2m • 1 change
Arrives next day

10h 7m • 1 change

6h 22m • 1 change

6h 17m • 1 change
Arrives next day

10h 37m • 1 change
Want to know about travelling from Penn State Harrisburg to Manhattan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Penn State Harrisburg to Manhattan. However, there are services departing from Penn State Harrisburg station and arriving at Manhattan station via New York Midtown. The journey, including transfers, takes approximately 7h 12m.
Penn State Harrisburg to Manhattan bus services, operated by Rabbit Transit, depart from Harrisburg Bus Station.
Penn State Harrisburg to Manhattan bus services, operated by Rabbit Transit, arrive at New York Midtown station.
The distance between Penn State Harrisburg and Manhattan is 243.7 km. The road distance is 378 km.
Flixbus USA operates a bus from Harrisburg Bus Station to New York Midtown twice daily. Tickets cost $35–60 and the journey takes 4h 10m.