The average bus between Penn Station and 22ND STREET station takes 5h 50m and the fastest bus takes 5h 12m. There is a bus service every few hours from Penn Station to 22ND STREET station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Penn Station and 22ND STREET station. The earliest departure is at 12:50 AM at night, and the last departure from Penn Station is at 10:42 PM which arrives into 22ND STREET station at 5:10 AM. All services require a transfer at EUTAW ST & PRESTON ST fs sb and take an average of 5h 50m. The schedules shown below are for the next available departures.


5h 53m • 2 changes


5h 35m • 2 changes


5h 54m • 2 changes


5h 12m • 2 changes


6h 23m • 2 changes


6h 53m • 2 changes


5h 29m • 2 changes


5h 27m • 2 changes


6h 23m • 2 changes


6h 53m • 2 changes


5h 29m • 2 changes


5h 27m • 2 changes


6h 23m • 2 changes


6h 53m • 2 changes


5h 29m • 2 changes


5h 27m • 2 changes
Want to know about travelling from Penn Station to 22ND STREET station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Penn Station to 22ND STREET station station. However, there are services departing from Penn Station station and arriving at 22ND STREET station via Newark Penn Station station. The journey, including transfers, takes approximately 5h 50m.
Penn Station to 22ND STREET station bus services, operated by Maryland Transit, depart from Baltimore Downtown Bus Station.
Penn Station to 22ND STREET station bus services, operated by Maryland Transit, arrive at Newark Penn Station.
The distance between Penn Station and 22ND STREET station is 260.8 km. The road distance is 317 km.
Flixbus USA operates a bus from Baltimore Downtown Bus Station to Newark Penn Station 5 times a day. Tickets cost $29–50 and the journey takes 3h 50m. Greyhound USA also services this route 3 times a day.