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Penn Station to Indianapolis buses

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Trip Overview

The average bus between Penn Station and Indianapolis takes 20h 13m and the fastest bus takes 19h 2m. The bus service runs several times per day from Penn Station to Indianapolis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

20h 13m
Duration
771 mi
Distance
$163
Average price
3 times a day
Frequency

Penn Station to Indianapolis bus times

Buses run 3 times a day between Penn Station and Indianapolis. The earliest departure is at 8:08 AM in the morning, and the last departure from Penn Station is at 9:59 PM which arrives into Indianapolis at 6:30 PM. All services require a transfer at MCCULLOH ST & PRESTON ST nb and take an average of 20h 13m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    Arrives next day

    Maryland TransitGreyhound USAGreyhound USA20h 43m • 2 changes
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    Arrives next day

    Maryland TransitFlixbus USAGreyhound USA20h 30m • 2 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Maryland TransitFlixbus USAGreyhound USA19h 2m • 2 changes
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    Arrives next day

    Maryland TransitGreyhound USAGreyhound USA20h 43m • 2 changes
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    Arrives next day

    Maryland TransitFlixbus USAGreyhound USA20h 30m • 2 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    Maryland TransitFlixbus USAGreyhound USA19h 15m • 2 changes
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    Arrives next day

    Maryland TransitGreyhound USAGreyhound USA20h 40m • 2 changes
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    Arrives next day

    Maryland TransitFlixbus USAGreyhound USA20h 50m • 2 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    Maryland TransitFlixbus USAGreyhound USA19h 12m • 2 changes
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    Arrives next day

    Maryland TransitGreyhound USAGreyhound USA20h 34m • 2 changes
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    Arrives next day

    Maryland TransitFlixbus USAGreyhound USA20h 47m • 2 changes

Departing Monday, November 16, 2026

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    Arrives next day

    Maryland TransitFlixbus USAGreyhound USA19h 2m • 2 changes
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    Arrives next day

    Maryland TransitGreyhound USAGreyhound USA20h 43m • 2 changes
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    Arrives next day

    Maryland TransitFlixbus USAGreyhound USA20h 30m • 2 changes

Departing Tuesday, November 17, 2026

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    Arrives next day

    Maryland TransitGreyhound USAGreyhound USA20h 1m • 2 changes
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    Arrives next day

    Maryland TransitGreyhound USAGreyhound USA20h 43m • 2 changes
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    Arrives next day

    Maryland TransitFlixbus USAGreyhound USA20h 30m • 2 changes

Departing Wednesday, November 18, 2026

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    Arrives next day

    Maryland TransitGreyhound USAGreyhound USA20h 1m • 2 changes
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    Arrives next day

    Maryland TransitGreyhound USAGreyhound USA20h 43m • 2 changes

Frequently asked questions

Want to know about travelling from Penn Station to Indianapolis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Penn Station to Indianapolis.ExpandLaunch map view
  • Distance: 771.4 mi
  • Duration: 20h 13m

What companies run services between Penn Station, MD, USA and Indianapolis, IN, USA?

You can take a vehicle from Penn Station to Indianapolis Union Station via MCCULLOH ST & PRESTON ST nb, HAINES ST & WARNER ST wb, Baltimore Downtown Bus Station, and Philadelphia Bus Station in around 19h 11m.

Operators