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Penn Station to Irvine buses

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Trip Overview

The bus between Penn Station and Irvine takes 3d 10h. The bus runs, on average, 2 times per week from Penn Station to Irvine. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3d 10h
Duration
2,825 mi
Distance
$523
Average price
Twice a week
Frequency

Penn Station to Irvine bus times

Buses run twice a week between Penn Station and Irvine. The earliest departure is at 11:09 AM in the morning, and the last departure from Penn Station is at 11:12 AM which arrives into Irvine at 6:19 PM. All services require a transfer at MCCULLOH ST & PRESTON ST nb and take an average of 3d 10h. The schedules shown below are for the next available departures.

Departing Saturday, October 10, 2026

  •  → 

    Arrives +3 days

    Maryland TransitGreyhound USAGreyhound USAGreyhound USAGreyhound USAOCTA3d 10h • 5 changes

Departing Sunday, October 11, 2026

  •  → 

    Arrives +3 days

    Maryland TransitGreyhound USAGreyhound USAGreyhound USAGreyhound USAOCTA3d 10h • 5 changes

Frequently asked questions

Want to know about travelling from Penn Station to Irvine? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Penn Station to Irvine.ExpandLaunch map view
  • Distance: 2,824.7 mi
  • Duration: 3d 10h

What companies run services between Penn Station, MD, USA and Irvine, CA, USA?

You can take a vehicle from Penn Station to Main-Harvard via MCCULLOH ST & PRESTON ST nb, HAINES ST & WARNER ST wb, Baltimore Downtown Bus Station, Harrisburg Bus Station, St Louis Bus Station, Los Angeles Union Station, Anaheim Regional Transportation Intermodal Center, and Artic - Dock 4 in around 2d 18h.

Operators