The average bus between Penn Station and Pittsburgh takes 8h 26m and the fastest bus takes 7h 22m. The bus service runs several times per day from Penn Station to Pittsburgh. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Penn Station and Pittsburgh. The earliest departure is at 12:13 AM at night, and the last departure from Penn Station is at 11:56 PM which arrives into Pittsburgh at 7:35 AM. All services require a transfer at EUTAW ST & PRESTON ST fs sb and take an average of 8h 26m. The schedules shown below are for the next available departures.

8h 19m • 1 change

10h 9m • 1 change

8h 9m • 1 change
Arrives next day

7h 39m • 1 change

7h 22m • 1 change

8h 14m • 1 change

9h 48m • 1 change

8h 10m • 1 change

7h 22m • 1 change

8h 14m • 1 change

9h 48m • 1 change

8h 10m • 1 change
Want to know about travelling from Penn Station to Pittsburgh? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Penn Station to Pittsburgh. However, there are services departing from Penn Station station and arriving at Pittsburgh station via Pittsburgh Intermodal Station station. The journey, including transfers, takes approximately 8h 26m.
Penn Station to Pittsburgh bus services, operated by Maryland Transit, depart from Baltimore Downtown Bus Station.
Penn Station to Pittsburgh bus services, operated by Maryland Transit, arrive at Pittsburgh Intermodal Station.
The distance between Penn Station and Pittsburgh is 314.7 km. The road distance is 451 km.
Greyhound USA operates a bus from Baltimore Downtown Bus Station to Pittsburgh Intermodal Station 4 times a day. Tickets cost $40–80 and the journey takes 5h 40m. Flixbus USA also services this route 4 times a week.