Penn Station to Pittsburgh Buses

Penn Station to Pittsburgh buses

Travel from

Search accommodation with Expedia

Trip Overview

The average bus between Penn Station and Pittsburgh takes 7h 49m and the fastest bus takes 6h 16m. The bus service runs several times per day from Penn Station to Pittsburgh. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

7h 49m
Duration: 272 mi
Distance: $57
Average price: 4 times a day
Frequency

Bus

best

Take the bus from Baltimore Downtown Bus Station to Pittsburgh Intermodal Stationbus Greyhound US0164 / ...

8h 31m

$42–77

Penn Station to Pittsburgh bus times

Buses run 4 times a day between Penn Station and Pittsburgh. The earliest departure is at 12:13 AM at night, and the last departure from Penn Station is at 11:56 PM which arrives into Pittsburgh at 7:35 AM. All services require a transfer at EUTAW ST & PRESTON ST fs sb and take an average of 7h 49m. The schedules shown below are for the next available departures.

Departing Saturday, October 31, 2026

12:13 AM → 7:35 AM
7h 22m • 1 change
5:08 AM → 1:30 PM
8h 22m • 1 change
11:08 AM → 5:25 PM
6h 17m • 1 change
3:38 PM → 11:50 PM
8h 12m • 1 change
Show more

Departing Sunday, November 1, 2026

5:11 AM → 1:30 PM
8h 19m • 1 change
8:56 AM → 5:45 PM
8h 49m • 1 change
11:11 AM → 6:15 PM
7h 4m • 1 change
3:41 PM → 11:50 PM
8h 9m • 1 change
Show more

Departing Monday, November 2, 2026

5:16 AM → 1:30 PM
8h 14m • 1 change
3:40 PM → 11:50 PM
8h 10m • 1 change

Departing Tuesday, November 3, 2026

12:13 AM → 7:35 AM
7h 22m • 1 change
5:16 AM → 1:30 PM
8h 14m • 1 change
3:40 PM → 11:50 PM
8h 10m • 1 change

Departing Wednesday, November 4, 2026

12:13 AM → 7:35 AM
7h 22m • 1 change
5:16 AM → 1:30 PM
8h 14m • 1 change
3:40 PM → 11:50 PM
8h 10m • 1 change

Departing Thursday, November 5, 2026

12:13 AM → 7:35 AM
7h 22m • 1 change
5:16 AM → 1:30 PM
8h 14m • 1 change
9:06 AM → 5:45 PM
8h 39m • 1 change
11:09 AM → 6:15 PM
7h 6m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Penn Station to Pittsburgh? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Penn Station to Pittsburgh buses

Trip Overview

Bus