The average bus between Penn Station and South Station takes 9h 26m and the fastest bus takes 8h 42m. The bus service runs several times per day from Penn Station to South Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Penn Station and South Station. The earliest departure is at 12:13 AM at night, and the last departure from Penn Station is at 9:58 PM which arrives into South Station at 7:50 AM. All services require a transfer at EUTAW ST & PRESTON ST fs sb and take an average of 9h 26m. The schedules shown below are for the next available departures.

9h 17m • 1 change
Arrives next day

8h 59m • 1 change
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10h 9m • 1 change

9h 14m • 1 change
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8h 42m • 1 change
Arrives next day

9h 52m • 1 change

9h 42m • 1 change
Arrives next day

8h 42m • 1 change
Arrives next day

9h 52m • 1 change

9h 42m • 1 change
Arrives next day

8h 42m • 1 change
Arrives next day

9h 52m • 1 change

9h 42m • 1 change
Arrives next day

8h 42m • 1 change
Arrives next day

9h 52m • 1 change
Want to know about travelling from Penn Station to South Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Penn Station to South Station. However, there are services departing from Penn Station station and arriving at South Station station via Boston. The journey, including transfers, takes approximately 9h 26m.
Penn Station to South Station bus services, operated by Maryland Transit, depart from Baltimore Downtown Bus Station.
Penn Station to South Station bus services, operated by Maryland Transit, arrive at Boston station.
The distance between Penn Station and South Station is 577.2 km. The road distance is 737 km.
Flixbus USA operates a bus from Baltimore Downtown Bus Station to Boston twice daily. Tickets cost $75–130 and the journey takes 8h 45m. Three other operators also service this route.