The average bus between Penn Station and Syracuse takes 10h 23m and the fastest bus takes 8h 57m. The bus service runs several times per day from Penn Station to Syracuse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Penn Station and Syracuse. The earliest departure is at 12:59 AM at night, and the last departure from Penn Station is at 3:06 PM which arrives into Syracuse at 1:15 AM. All services require a transfer at MCCULLOH ST & PRESTON ST nb and take an average of 10h 23m. The schedules shown below are for the next available departures.


12h 8m • 2 changes


9h 46m • 2 changes


8h 59m • 2 changes
Arrives next day


10h 8m • 2 changes


12h 35m • 2 changes


9h 46m • 2 changes


8h 59m • 2 changes
Arrives next day


10h 8m • 2 changes


12h 35m • 2 changes


9h 46m • 2 changes


8h 59m • 2 changes
Arrives next day


10h 8m • 2 changes


12h 35m • 2 changes


9h 46m • 2 changes


8h 59m • 2 changes
Arrives next day


10h 8m • 2 changes
Want to know about travelling from Penn Station to Syracuse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Penn Station to Syracuse. However, there are services departing from Penn Station station and arriving at Syracuse station via Newark Penn Station station. The journey, including transfers, takes approximately 10h 23m.
Penn Station to Syracuse bus services, operated by Maryland Transit, depart from Baltimore Downtown Bus Station.
Penn Station to Syracuse bus services, operated by Maryland Transit, arrive at Syracuse Bus Station.
The distance between Penn Station and Syracuse is 417.8 km. The road distance is 683 km.
You can take a vehicle from Penn Station to Syracuse Bus Station via MCCULLOH ST & PRESTON ST nb, HAINES ST & WARNER ST wb, Baltimore Downtown Bus Station, and Newark Penn Station in around 10h 50m.